Corticotropin releasing factor impairs sustained attention in male and female rats
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چکیده
منابع مشابه
Role of Corticotropin Releasing Factor 1 Signaling in Cocaine Seeking during Early Extinction in Female and Male Rats
Locus coeruleus norepinephrine (LC-NE) and corticotropin releasing factor (CRF) neurons are involved in stress responses, including stress's ability to drive drug relapse. Previous animal studies indicate that female rats exhibit greater drug seeking than male rats during initial drug abstinence. Moreover, females are more sensitive to the effect of stress to drive drug seeking than males. Fina...
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Exposure to stressors facilitates the formation of social preferences in monogamous male prairie voles (Microtus ochrogaster). In the present study, the hypothesis was tested that treatment with corticotropin-releasing factor (CRF), a neuropeptide released during stress, is capable of inducing social preferences in male prairie voles. The effects of five doses of CRF (0.01, 0.1, 1.0, 10 and 100...
متن کاملCorticotropin-releasing Factor
Introduction Immunoreactivity similar to that of corticotropin-releasing factor (CRF) is found in regions of the central nervous system that modulate autonomic responses, including gastrointestinal functions. We examined the central nervous system effects of ovine CRF on gastric acid secretion in conscious dogs. Male beagle dogs (11-13 kg) were fitted with chronic intracerebroventricular cannul...
متن کاملCorticotropin releasing factor in neuroplasticity.
Stress is among the strongest signals promoting neuroplasticity: Stress signals, indicating real or perceived danger, lead to alterations of neuronal function and often structure, designed to adapt to the changed conditions and promote survival. Corticotropin releasing factor (CRF) is expressed and released in several types of neuronal populations that are involved in cognition, emotion and the...
متن کاملThe Effects Of Adolescent Binge Drinking On Corticotropin-Releasing Factor Cells In The Amygdala And Social Predictors Of Alcohol Intake In Male And Female Rats
iii ACKNOWLEDGEMENTS First I would like to thank my advisor, Dr. Heather Richardson, for all of her support, patience, and guidance. Her belief in me is what made all of this possible and I will be forever grateful to her. I would also like to thank my committee members, Drs. Matt Davidson and Jeffrey Podos for continued guidance. Thank you also to Dr. Brian Whitcomb for his expertise and guida...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2016
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2015.08.023